The most sensitive and specific imaging Method for the localization of a parathyroid Adenoma is:
A. CT of the neck
B. MRI of neck and chest
C. Thallium technetium pertechnetate scan
D. Sestamibi scan
Answer: D
Sestamibi scan is considered to be the most sensitive and specific imaging method for the localization of a parathyroid adenoma. Sestamibi (technetium-99m methoxyisobutylisonitrile) is a radiopharmaceutical that is taken up specifically by parathyroid cells, allowing for high-resolution imaging of parathyroid tumors. Other imaging methods such as ultrasonography and CT scan of the neck may also be used but Sestamibi scan is considered to be the most sensitive and specific method for parathyroid adenoma localization.
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