What is the treatment of choice for pituitary prolactinomas?
A. Surgical intervention
B. Radiotherapy
C. Combined surgical and radiotherapy approach
D. Dopamine agonist therapy
The treatment of choice for pituitary prolactinomas, which are benign tumors of the pituitary gland that secrete prolactin, is Dopamine agonists. These medications work by stimulating dopamine receptors in the pituitary gland, thereby inhibiting prolactin secretion.
Surgery (Choice A) may be considered for large or symptomatic prolactinomas that do not respond to medical therapy or in cases of pituitary apoplexy (acute hemorrhage or infarction of the pituitary gland).
Radiotherapy (Choice B) is typically reserved for cases where surgery and medical therapy have failed, or in cases of aggressive or refractory tumors.
Surgery followed by radiotherapy (Choice C) may be considered in selected cases, but it is not the primary treatment of choice for prolactinomas. Dopamine agonists are typically the first-line treatment and are effective in reducing tumor size and normalizing prolactin levels in most cases.
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