Surgery MCQ 93

One of the following blood group is a known Predisposing factor for Gastric Carcinoma:

A. Blood group 0

B. Blood group B

C. Blood group A

D. Blood group AB

Answer: C (GS)

The Correct Answer is Blood group A (ref)

Exogenous risk factors:

• Diet rich in nitrates and/or salts (e.g., dried foods, foods preserved by curing or smoking)  and low in fresh vegetables containing antioxidants [4]
• H. pylori infection 
• Nicotine use 
• Epstein-Barr virus 
• Low socioeconomic status
• Obesity

Endogenous risk factors

• Gastric conditions
• Chronic atrophic gastritis and associated pernicious anemia
• Achlorhydria (e.g., due to Ménétrier disease)
• Gastric ulcers
• Partial gastrectomy
• Adenomatous gastric polyps
• Gastroesophageal reflux disease
• Hereditary factors
• Positive family history
• Blood type A 
• Hereditary nonpolyposis colorectal cancer

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